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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| GGFG | Doxorubicin |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01630 |
| Smiles | |
| Molecular weight | 1103.42 |
| Molecular formula | C61H61N5O15 |
| Chemical name | Peptide information |
| Sequence (one letter) | GGFG |
| Length | 4 |
| Peptide name | tetrapeptide |
| External ID | |
|---|---|
| CAS number | 173723-58-5 |
| Other information | |
|---|---|
| Application | Antitumor therapy |
| Additional function | Improved effect |
| Pharmacological class | anticancer |
| Conjugate type | amide |
| Linker | no |
| Small molecule | Doxorubicin |
| Small molecule CAS | 23214-92-8 |
| Small molecule structure | |
| Structure method | 1H NMR |
| NMR solvent | CD3OD |
| Calculated properties | |
|---|---|
| LogP | 4.72895 |
| Rotatable bonds | 20 |
| H bond donor | 10 |
| H bond acceptor | 16 |
| Polar surface area (PSA) | 308.48000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Synthesis of carboxymethylpullulan-peptide-doxorubicin conjugates and their properties | 1995 | Nogusa, Hideo; Yano, Toshiro; Okuno, Satoshi; Hamana, Hiroshi; Inoue, Kazuhiro | Chemical & Pharmaceutical Bulletin | ||
