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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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| RKQMAVKKYLN | 3H-Indolium, 5-carboxy-2-[7-[1,3-dihydro-3,3-dimethyl-1-(4-sulfobutyl)-2H-indol-2-ylidene]-1,3,5-heptatrien-1-yl]-3,3-dimethyl-1-(4-sulfobutyl)-, inner salt |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01551 |
| Smiles | |
| Molecular weight | 2057.04 |
| Molecular formula | C97H150N21O22S3 |
| Chemical name | Peptide information |
| Sequence (one letter) | RKQMAVKKYLN |
| Length | 11 |
| Peptide name | vasoactive intestinal peptide (VIP) fragment |
| External ID | |
|---|---|
| CAS number | 273383-48-5 |
| Other information | |
|---|---|
| Application | Synthesis and analytics |
| Additional function | Potential fluorescent contrast agents targeted to tumor-specific receptors |
| Pharmacological class | other |
| Conjugate type | amide |
| Linker | no |
| Small molecule | 3H-Indolium, 5-carboxy-2-[7-[1,3-dihydro-3,3-dimethyl-1-(4-sulfobutyl)-2H-indol-2-ylidene]-1,3,5-heptatrien-1-yl]-3,3-dimethyl-1-(4-sulfobutyl)-, inner salt |
| Small molecule CAS | 208243-29-2 |
| Structure method | RP-HPLC, MALDI-TOF MS |
| Calculated properties | |
|---|---|
| LogP | -10.45419 |
| Rotatable bonds | 66 |
| H bond donor | 23 |
| H bond acceptor | 29 |
| Polar surface area (PSA) | 718.76000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Highly parallel nano-synthesis of cleavable peptide-dye conjugates on cellulose membranes | 2000 | Licha, Kai; Bhargava, Sarah; Rheinlander, Christiane; Becker, Andreas; Schneider-Mergener, Jens; Volkmer-Engert, Rudolf | Tetrahedron Letters | ||
