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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| GRKKRRQRRRPPQ | PEG | Porphine derivative |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01299 |
| Smiles | |
| Molecular weight | 3075.56 |
| Molecular formula | C142H206N42O36 |
| Chemical name | Peptide information |
| Sequence (one letter) | GRKKRRQRRRPPQ |
| Length | 13 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 880760-18-9 |
| Other information | |
|---|---|
| Application | Anticancer therapy, photosensitizer |
| Additional function | Improving solubility an cell penetration |
| Pharmacological class | anticancer |
| Conjugate type | amide |
| Linker | N/A |
| Linker Type | PEG |
| Small molecule | Porphine derivative |
| Small molecule CAS | 880760-16-7 |
| Structure method | 1H NMR, HPLC |
| NMR solvent | D2O |
| Calculated properties | |
|---|---|
| LogP | -13.77138 |
| Rotatable bonds | 106 |
| H bond donor | 41 |
| H bond acceptor | 58 |
| Polar surface area (PSA) | 1251.65000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Peptide-Mediated Cell Transport of Water Soluble Porphyrin Conjugates | 2006 | Sibrian-Vazquez, Martha; Jensen, Timothy J.; Hammer, Robert P.; Vicente, M. Graca H. | Journal of Medicinal Chemistry | ||
