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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| GGGGRGDS | PEG | ureidopyrimidinone (UPy) |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00577 |
| Smiles | |
| Inchi Key | InChIKey=NTWPLZLUZPFGDT-VPMCDZTMSA-N |
| Molecular weight | 1659.88 |
| Molecular formula | C69H121N21O26 |
| Chemical name | Peptide information |
| Sequence (one letter) | GGGGRGDS |
| Length | 8 |
| Peptide name | N-terminal aldehyde peptide |
| External ID | |
|---|---|
| CAS number | 1358996-36-7 |
| Other information | |
|---|---|
| Application | Synthesis, self-assembly, control over the position and availability of bioactive molecules in biomaterials |
| Additional function | Possible application in regenerative medicine |
| Conjugate type | amide |
| Linker | N/A |
| Linker Type | PEG |
| Small molecule | ureidopyrimidinone (UPy) |
| Small molecule CAS | 1358996-31-2 |
| Small molecule structure | |
| Calculated properties | |
|---|---|
| LogP | -10.54259 |
| Rotatable bonds | 73 |
| H bond donor | 20 |
| H bond acceptor | 31 |
| Polar surface area (PSA) | 675.17000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Modular synthesis of supramolecular ureidopyrimidinone-peptide conjugates using an oxime ligation strategy | 2012 | Kieltyka, Roxanne E.; Bastings, Maartje M. C.; van Almen, Geert C.; Besenius, Pol; Kemps, Erwin W. L.; Dankers, Patricia Y. W. | Chemical Communications | ||
