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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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| HQRLF | 3-amino-(3β,5β)-Cholan-24-oic aci methyl ester |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00242 |
| Smiles | |
| Inchi Key | InChIKey=IMWRLAMERDEGKH-TVPXYITDSA-N |
| Molecular weight | 2086.09 |
| Molecular formula | C125H147N13O14S |
| Chemical name | Peptide information |
| Sequence (one letter) | HQRLF |
| Length | 5 |
| Peptide name | pentapeptide |
| External ID | |
|---|---|
| CAS number | 1781222-51-2 |
| Other information | |
|---|---|
| Application | Synthesis, incorporation of complex N-substituents at both termini and at internal positions |
| Additional function | Modifications of biologically relevant peptides: fluorescent labeling, PEGylation, glycosylation, etc. |
| Pharmacological class | other |
| Conjugate type | sulfonamide |
| Linker | no |
| Small molecule | 3-amino-(3β,5β)-Cholan-24-oic aci methyl ester |
| Small molecule CAS | 106697-50-1 |
| Small molecule structure | |
| Calculated properties | |
|---|---|
| LogP | 19.67298 |
| Rotatable bonds | 43 |
| H bond donor | 9 |
| H bond acceptor | 15 |
| Polar surface area (PSA) | 385.13000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Aminocatalysis-Mediated on-Resin Ugi Reactions: Application in the Solid-Phase Synthesis of N-Substituted and Tetrazolo Lipopeptides and Peptidosteroids | 2015 | Morales, Fidel E.; Garay, Hilda E.; Munoz, Daniela F.; Augusto, Yarelys E.; Otero-Gonzalez, Anselmo J.; Reyes Acosta, Osvaldo; Rivera, Daniel G. | Organic Letters | ||
